New NDV-H5NX avian influenza vaccine has potential for mass vaccination of poultry

Date:January 7, 2016

Source:Kansas State University

A team of researchers at Kansas State University, in collaboration with Garcia-Sastre of the Icahn School of Medicine at Mount Sinai, has developed a vaccine that protects poultry from multiple strains of avian influenza found in the U.S., including H5N1, H5N2 and H5N8. The vaccine has the potential to be administered through water or into embryonated eggs, making it easier for poultry producers to vaccinate flocks.

The vaccine, called NDV-H5Nx, protects chickens and likely other poultry against the three recently introduced U.S. avian influenza strains H5N1, H5N2 and H5N8, as well as against Newcastle disease virus -- a virus that naturally affects poultry. Avian influenza killed millions of chickens and turkeys in the U.S. in spring and summer 2015, leading to billions in lost revenue for the U.S. poultry industry.

The NDV-H5Nx vaccine also has the potential to be administered to millions of birds at a time through water, said Jürgen Richt, Regents distinguished professor of veterinary medicine, director of the U.S. Department of Homeland Security's Center of Excellence for Emerging and Zoonotic Animal Diseases at Kansas State University and one of the researchers involved in the discovery.

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